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  Dendritic structural plasticity

Tavosanis, G. (2012). Dendritic structural plasticity. DEVELOPMENTAL NEUROBIOLOGY, 72(1), 73-86. doi:10.1002/dneu.20951.

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資料種別: 学術論文

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 作成者:
Tavosanis, Gaia1, 2, 著者           
所属:
1Research Group: Dendrite Differentiation / Tavosanis, MPI of Neurobiology, Max Planck Society, ou_1113561              
2External Organizations, ou_persistent22              

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キーワード: RETINAL GANGLION-CELLS; HONEYBEE MUSHROOM BODY; ADULT VISUAL-CORTEX; VIVO TIME-LAPSE; IN-VIVO; PYRAMIDAL NEURONS; NMDA RECEPTOR; FUNCTIONAL ARCHITECTURE; SYNAPTIC ORGANIZATION; MORPHOLOGICAL-CHANGESDevelopmental Biology; Neurosciences; dendrite; neuron; activity-dependent; plasticity; learning and memory;
 要旨: Dendrites represent the compartment of neurons primarily devoted to collecting and computating input. Far from being static structures, dendrites are highly dynamic during development and appear to be capable of plastic changes during the adult life of animals. During development, it is a combination of intrinsic programs and external signals that shapes dendrite morphology; input activity is a conserved extrinsic factor involved in this process. In adult life, dendrites respond with more modest modifications of their structure to various types of extrinsic information, including alterations of input activity. Here, the author reviews classical and recent evidence of dendrite plasticity in invertebrates and vertebrates and current progress in the understanding of the molecular mechanisms that underlie this plasticity. Importantly, some fundamental questions such as the functional role of dendrite remodeling and the causal link between structural modifications of neurons and plastic processes, including learning, are still open. (c) 2011 Wiley Periodicals, Inc. Develop Neurobiol 72: 7386, 2012

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言語: eng - English
 日付: 2012-01
 出版の状態: 出版
 ページ: 14
 出版情報: -
 目次: -
 査読: -
 識別子(DOI, ISBNなど): ISI: 000298062000006
DOI: 10.1002/dneu.20951
 学位: -

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出版物名: DEVELOPMENTAL NEUROBIOLOGY
種別: 学術雑誌
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出版社, 出版地: COMMERCE PLACE, 350 MAIN ST, MALDEN 02148, MA USA : WILEY-BLACKWELL
ページ: - 巻号: 72 (1) 通巻号: - 開始・終了ページ: 73 - 86 識別子(ISBN, ISSN, DOIなど): ISSN: 1932-8451