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  Autoimmunity's next top models

Wekerle, H., Fluegel, A., Fugger, L., Schett, G., & Serreze, D. (2012). Autoimmunity's next top models. NATURE MEDICINE, 18(1), 66-70.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-41B1-C Version Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-41B2-A
Genre: Journal Article

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 Creators:
Wekerle, Hartmut1, Author              
Fluegel, Alexander2, Author
Fugger, Lars2, Author
Schett, Georg2, Author
Serreze, David2, Author
Affiliations:
1Department: Neuroimmunology / Wekerle, MPI of Neurobiology, Max Planck Society, ou_1113547              
2External Organizations, ou_persistent22              

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Free keywords: MYELIN BASIC-PROTEIN; PROGRESSIVE MULTIFOCAL LEUKOENCEPHALOPATHY; MULTIPLE-SCLEROSIS; T-CELLS; RHEUMATOID-ARTHRITIS; ANIMAL-MODELS; NOD MICE; HEALTHY-INDIVIDUALS; CROSS-REACTIVITY; HUMAN IMMUNOLOGYBiochemistry & Molecular Biology; Cell Biology; Medicine, Research & Experimental;
 Abstract: Animal models are indispensable for studying disease pathogenesis and discovering new treatments for human organ-specific autoimmune diseases. However, there is a need of more refined paradigms for these models. Ideally, a small-animal model should represent the clinical features of human disease in their entirety. Disease in the animals should develop spontaneously, should be followed over an extended period of time and should involve the genetic, molecular and cellular elements that contribute to human pathogenesis.

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Language(s): eng - English
 Dates: 2012-01
 Publication Status: Published in print
 Pages: 5
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: ISI: 000299018600030
 Degree: -

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Title: NATURE MEDICINE
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: 75 VARICK ST, 9TH FLR, NEW YORK, NY 10013-1917 USA : NATURE PUBLISHING GROUP
Pages: - Volume / Issue: 18 (1) Sequence Number: - Start / End Page: 66 - 70 Identifier: ISSN: 1078-8956