English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
  Base-pair mapping by chemical force microscopy on nucleobase self-assembled monolayers

Ijiro, K., Sunami, H., Arai, K., Matsumoto, J., Karthaus, O., Kraemer, S., et al. (2002). Base-pair mapping by chemical force microscopy on nucleobase self-assembled monolayers. Colloids and Surfaces A-Physicochemical and Engineering Aspects, 198-200, 677-682.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Ijiro, K.1, Author           
Sunami, H., Author
Arai, K., Author
Matsumoto, J., Author
Karthaus, O., Author
Kraemer, S., Author
Mittler, Silvia1, Author           
Nishi, N., Author
Juskowiak, B., Author
Takenaka, S., Author
Knoll, Wolfgang1, Author           
Shimomura, M., Author
Affiliations:
1MPI for Polymer Research, Max Planck Society, ou_1309545              

Content

show
hide
Free keywords: self-assembled monolayer; nucleic acid base; chemical force mapping; base pair; hydrogen bond
 Abstract: Self-assembled monolayers (SAMs) of double-chain disulfide derivatives of nucleobases (adenine and thymine) were formed on Au substrates in order to measure complementary hydrogen bonding by chemical force microscopy at the interfaces. Surface plasmon resonance measurements indicated that the formation of the nucleobase SAMs on Au surface was completed within 80 min. To measure adhesion force by atomic force microscopy (AFM), Au- coated AFM tips were modified with the nucleobase SAMs, too. SAM-modified An substrates micro-patterned on quartz substrates were prepared for adhesion force mapping. The adhesion force between the complementary nucleobases is larger than that of the non-complementary combination. Electrochemical detection using a redox-intercalator was demonstrated for hybridization of single-stranded polynucleic acid with the nucleobase SAMs modified on Au electrodes. (C) 2002 Elsevier Science B.V. All rights reserved.

Details

show
hide
Language(s): eng - English
 Dates: 2002-02-18
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: No review
 Identifiers: eDoc: 28517
ISI: 000174495800081
Other: P-02-42
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Colloids and Surfaces A-Physicochemical and Engineering Aspects
  Alternative Title : Colloid Surf. A-Physicochem. Eng. Asp.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 198-200 Sequence Number: - Start / End Page: 677 - 682 Identifier: ISSN: 0927-7757