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  Late motor decline after accomplished remyelination: Impact for progressive multiple sclerosis.

Manrique-Hoyos, N., Jürgens, T., Gronborg, M., Kreutzfeld, M., Schedensack, M., Kuhlmann, T., et al. (2012). Late motor decline after accomplished remyelination: Impact for progressive multiple sclerosis. Annals of Neurology, 71(2), 227-244. doi:10.1002/ana.22681.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-83C0-F Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-E596-C
Genre: Journal Article

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 Creators:
Manrique-Hoyos, N., Author
Jürgens, T., Author
Gronborg, M., Author
Kreutzfeld, M., Author
Schedensack, M., Author
Kuhlmann, T., Author
Schrick, C., Author
Brück, W., Author
Urlaub, H.1, Author              
Simons, M., Author
Merkler, D., Author
Affiliations:
1Research Group of Bioanalytical Mass Spectrometry, MPI for biophysical chemistry, Max Planck Society, ou_578613              

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 Abstract: M ultiple sclerosis (MS) is the most common disabling neurological disease in young adults (reviewed in Friese and colleagues, 1 Trapp and colleagues, 2 and Nose- worthy and colleagues 3 ). Disability often becomes apparent as a result of repeated attacks, followed by par- tial or complete remission of neurological symptoms (relapsing-remitting MS [RRMS]), which in turn is fol- lowed by a phase of gradually worsening clinical symp- toms (secondary progressive MS [SPMS]). Moreover, some MS patients show a steady neurological decline even in the absence of acute attacks (primary progressive MS [PPMS]).

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Language(s): eng - English
 Dates: 2012-02-242012-02
 Publication Status: Published in print
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 Table of Contents: -
 Rev. Method: Peer
 Identifiers: DOI: 10.1002/ana.22681
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Title: Annals of Neurology
Source Genre: Journal
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Pages: - Volume / Issue: 71 (2) Sequence Number: - Start / End Page: 227 - 244 Identifier: -