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  Enhancing the Thermal Robustness of an Enzyme by Directed Evolution: Least Favorable Starting Points and Inferior Mutants Can Map Superior Evolutionary Pathways

Gumulya, Y., & Reetz, M. T. (2011). Enhancing the Thermal Robustness of an Enzyme by Directed Evolution: Least Favorable Starting Points and Inferior Mutants Can Map Superior Evolutionary Pathways. ChemBioChem, 12, 2502-2510. doi:10.1002/cbic.201100412.

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 Creators:
Gumulya, Y.1, Author              
Reetz, M. T.1, Author              
Affiliations:
1Research Department Reetz, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445588              

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Free keywords: directed evolution; enzymes; epoxide hydrolases; quasi-species; neutral drift
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Language(s): eng - English
 Dates: 2011
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 577732
DOI: 10.1002/cbic.201100412
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Title: ChemBioChem
  Alternative Title : ChemBioChem
Source Genre: Journal
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Publ. Info: MALDEN : WILEY-BLACKWELL
Pages: - Volume / Issue: 12 Sequence Number: - Start / End Page: 2502 - 2510 Identifier: ISSN: 1439-4227