English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
 
 
DownloadE-Mail
 Local TagsRelease HistoryDetailsSummary
  Synthesis, structures and anti-malaria activity of some gold(I) phosphine complexes containing seleno- and thiosemicarbazonato ligands

Molter, A., Rust, J., Lehmann, C. W., Deepa, G., Chiba, P., & Mohr, F. (2011). Synthesis, structures and anti-malaria activity of some gold(I) phosphine complexes containing seleno- and thiosemicarbazonato ligands. Dalton Transactions, 40(38), 9810-9820. doi:10.1039/C1DT10885A.

Item is

 

show all hide all

Basic

show hide
Item Permalink: https://hdl.handle.net/11858/00-001M-0000-000F-8C5D-3 Version Permalink: https://hdl.handle.net/21.11116/0000-0007-1E40-0
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Molter, Anja1, Author
Rust, Jörg2, Author           
Lehmann, Christian W.2, Author           
Deepa, Ganesh3, Author
Chiba, Peter3, Author
Mohr, Fabian1, Author
Affiliations:
1Fachbereich C - Anorganische Chemie, Bergische Universität Wuppertal, Wuppertal, Germany, ou_persistent22              
2Service Department Lehmann (EMR), Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445625              
3Institute of Medical Chemistry, Medical University of Vienna, Vienna, Austria, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: A series of both mono- and dinuclear gold(I) phosphine complexes containing monoanionic seleno- and thiosemicarbazones as ligands were prepared and fully characterized by spectroscopic methods and, in some cases, by single crystal X-ray diffraction. The in vitro anti-malaria activity of some of these compounds was investigated in chloroquine sensitive strains of Plasmodium falciparum. The IC50 results show that the sulfur containing compounds exhibit activity similar to that of chloroquine, whilst the selenium derivatives display only moderate anti-malaria activity.

Details

show
hide
Language(s): eng - English
 Dates: 2011-08-302011-10-14
 Publication Status: Issued
 Pages: 11
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1039/C1DT10885A
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Dalton Transactions
  Abbreviation : Dalton Trans.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Cambridge, UK : Royal Society of Chemistry
Pages: - Volume / Issue: 40 (38) Sequence Number: - Start / End Page: 9810 - 9820 Identifier: ISSN: 1477-9226
CoNE: https://pure.mpg.de/cone/journals/resource/954925269323