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  Towards a Practical Brønsted Acid Catalyzed and Hantzsch Ester Mediated Asymmetric Reductive Amination of Ketones with Benzylamine

Wakchaure, V. N., Nicoletti, M., Ratjen, L., & List, B. (2010). Towards a Practical Brønsted Acid Catalyzed and Hantzsch Ester Mediated Asymmetric Reductive Amination of Ketones with Benzylamine. Synlett, (18), 2708-2710. doi:10.1055/s-0030-1259003.

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 Creators:
Wakchaure, Vijay N.1, Author              
Nicoletti, Marcello1, Author              
Ratjen, Lars1, Author              
List, Benjamin1, Author              
Affiliations:
1Research Department List, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445585              

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Free keywords: benzylamine; Hantzsch ester; reductive amination; organocatalysis; chiral amines; Brønsted acids
 Abstract: We report the use of benzylamine as the amine component in Hantzsch ester mediated and chiral Brønsted acid catalyzed enantioselective reductive aminations of ketones. The method is noteworthy because the benzyl group is easily removable, and amine product purification is achieved through Hantzsch ester oxidation product removal via basic hydrolysis.

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Language(s): eng - English
 Dates: 2010-08-242010-10-142010-11-01
 Publication Status: Published in print
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1055/s-0030-1259003
 Degree: -

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Title: Synlett
  Abbreviation : Synlett
Source Genre: Journal
 Creator(s):
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Publ. Info: Stuttgart : Georg Thieme Verlag
Pages: - Volume / Issue: (18) Sequence Number: - Start / End Page: 2708 - 2710 Identifier: ISSN: 0936-5214
CoNE: https://pure.mpg.de/cone/journals/resource/954925570856