ausblenden:
Schlagwörter:
asymmetric catalysis; chemoselectivity; enantioselectivity; hydrogenation; organocatalysis
Zusammenfassung:
Selective reduction without metals: An imidazolidinone salt effectively catalyzes the highly enantioselective biomimetic transfer hydrogenation of α,β‐unsaturated aldehydes to give the saturated analogues using a synthetic dihydropyridine cofactor (see scheme). Remarkably only one enantiomer forms regardless of the configuration of the enal starting material.
