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  Efficient Asymmetric Hydrogenation of Pyridines

Glorius, F., Spielkamp, N., Holle, S., Goddard, R., & Lehmann, C. W. (2004). Efficient Asymmetric Hydrogenation of Pyridines. Angewandte Chemie International Edition, 43(21), 2850-2852. doi:10.1002/anie.200453942.

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 Creators:
Glorius, Frank1, Author              
Spielkamp, Nick2, Author              
Holle, Sigrid3, Author              
Goddard, Richard4, Author              
Lehmann, Christian W.4, Author              
Affiliations:
1Research Group Glorius, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445602              
2Research Department Schüth, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445589              
3Research Group Alcarazo, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445592              
4Service Department Lehmann (EMR), Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445625              

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Free keywords: asymmetric synthesis; chiral auxiliaries; heterogeneous catalysis; hydrogenation; piperidines
 Abstract: Up to four stereocenters can be created efficiently in a single step by the asymmetric hydrogenation of oxazolidinone‐substituted pyridines (see scheme). Furthermore, selective chirality transfer and nondestructive cleavage of the chiral auxiliary occur under the same reaction conditions, making an additional cleavage step unnecessary.

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Language(s): eng - English
 Dates: 2004-05-17
 Publication Status: Published in print
 Pages: 3
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1002/anie.200453942
 Degree: -

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Title: Angewandte Chemie International Edition
  Abbreviation : Angew. Chem., Int. Ed.
Source Genre: Journal
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Publ. Info: Weinheim : Wiley-VCH
Pages: - Volume / Issue: 43 (21) Sequence Number: - Start / End Page: 2850 - 2852 Identifier: ISSN: 1433-7851
CoNE: https://pure.mpg.de/cone/journals/resource/1433-7851