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  Mitochondrial cristae revealed with focused light.

Schmidt, R., Wurm, C., Punge, A., Egner, A., Jakobs, S., & Hell, S. W. (2009). Mitochondrial cristae revealed with focused light. Nano Letters, 9(6), 2508-2510. doi:10.1021/nl901398t.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-9CE6-1 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0028-8319-B
Genre: Journal Article

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 Creators:
Schmidt, R.1, Author              
Wurm, C.1, Author              
Punge, A.1, Author              
Egner, A.1, Author              
Jakobs, S.2, Author              
Hell, S. W.1, Author              
Affiliations:
1Department of NanoBiophotonics, MPI for biophysical chemistry, Max Planck Society, ou_578627              
2Research Group of Mitochondrial Structure and Dynamics, MPI for biophysical chemistry, Max Planck Society, ou_578566              

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 Abstract: Because of the diffraction resolution barrier, optical microscopes have so far failed in visualizing the mitochondrial cristae, that is, the folds of the inner membrane of this 200 to 400 nm diameter sized tubular organelle. Realizing a ∼30 nm isotropic subdiffraction resolution in isoSTED fluorescence nanoscopy, we have visualized these essential structures in the mitochondria of intact cells. We find a pronounced heterogeneity in the cristae arrangements even within individual mitochondrial tubules.

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Language(s): eng - English
 Dates: 2009-05-212009
 Publication Status: Published in print
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 Rev. Method: Peer
 Identifiers: DOI: 10.1021/nl901398t
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Title: Nano Letters
Source Genre: Journal
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Pages: - Volume / Issue: 9 (6) Sequence Number: - Start / End Page: 2508 - 2510 Identifier: -