English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  New drug for inhibiting aggregation of proteins involved in diseases linked to protein aggregation and/or neurodegenerative diseases.
Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-D1F6-C Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0027-D58E-3
Genre: Patent

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Giese, A., Author
Bertsch, U., Author
Kretzschmar, H., Author
Habeck, M., Author
Hirschberger, T., Author
Tavan, P., Author
Griesinger, C.1, Author              
Leonov, A.1, Author              
Ryazanov, S.1, Author              
Weber, P., Author
Affiliations:
1Department of NMR-Based Structural Biology, MPI for biophysical chemistry, Max Planck Society, ou_578567              

Content

show
hide
Free keywords: -
 Abstract: The present invention relates to a compound represented by formula (E). The present invention also relates to a compound represented by the formula (E) for use in the treatment or prevention of diseases linked to protein aggregation and/or neurodegenerative diseases. Moreover, the present invention relates to pharmaceutical and diagnostic compositions comprising the compound of the invention as well as to a kit. Furthermore, the present invention relates to a method of imaging deposits of aggregated protein. A kit for preparing a detectably labelled compound of the present invention is also disclosed. Formula (E) wherein X, Y and L are independently nondirectionally selected from -C(R1)(R2)-, -C(R3)=, -N(R4)-, -N=, -N+(R5)=, -O- and -S-; M and Z are independently nondirectionally selected from formula (I) and formula (II).

Details

show
hide
Language(s):
 Dates: 2009-06-092010-01-07
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: Patent Nr.: WO/2010/00372
Patent Application Nr.: PCT/EP2009/004144
 Degree: -

Event

show

Legal Case

show

Project information

show

Source

show