English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  MHC-based mate choice combines good genes and maintenance of MHC polymorphism

Eizaguirre, C., Yeates, S. E., Lenz, T. L., Kalbe, M., & Milinski, M. (2009). MHC-based mate choice combines good genes and maintenance of MHC polymorphism. Molecular Ecology, 18(15), 3316-3329. doi:10.1111/j.1365-294X.2009.04243.x.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-D5A4-8 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-D5A5-6
Genre: Journal Article

Files

show Files
hide Files
:
Eizaguirre_2009.pdf (Publisher version), 429KB
 
File Permalink:
-
Name:
Eizaguirre_2009.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Evolutionary Biology, Plön; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Eizaguirre, Christophe1, Author              
Yeates, Sarah E.1, Author              
Lenz, Tobias L.1, Author              
Kalbe, Martin2, Author              
Milinski, Manfred1, Author              
Affiliations:
1Department Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445634              
2Research Group Parasitology, Department Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445643              

Content

show
hide
Free keywords: female mate choice; good genes; major histocompatibility complex; MHC polymorphism; optimality; reproductive success
 Abstract: Polymorphic genes of the major histocompatibility complex (MHC) are regarded as essential genes for individual fitness under conditions of natural and sexual selection. To test this hypothesis, we investigated the ultimate individual fitness trait — that of reproductive success. We used three-spined sticklebacks (Gasterosteus aculeatus) in seminatural enclosures, located in natural breeding areas where the experimental fish had been caught. During their reproductive period, fish were exposed continuously to their natural sympatric parasites. By genotyping almost 4000 eggs with nine microsatellites, we determined parenthood and inferred female mating decision. We found that with reference to their own MHC profile, female sticklebacks preferred to mate with males sharing an intermediate MHC diversity. In addition, males with a specific MHC haplotype were bigger and better at fighting a common parasite (Gyrodactylus sp.). This translated directly into Darwinian fitness since fish harbouring this specific MHC haplotype were more likely to be chosen and had a higher reproductive output. We conclude that females also based their mating decision on a specific MHC haplotype conferring resistance against a common parasite. This identifies and supports 'good genes'. We argue that such an interaction between host and parasite driving assortative mating is not only a prerequisite for negative frequency-dependent selection — a potential mechanism to explain the maintenance of MHC polymorphism, but also potentially speciation.

Details

show
hide
Language(s): eng - English
 Dates: 2009-06-11
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: eDoc: 433995
DOI: 10.1111/j.1365-294X.2009.04243.x
Other: 2711/S 39024
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Molecular Ecology
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 18 (15) Sequence Number: - Start / End Page: 3316 - 3329 Identifier: ISSN: 0962-1083 (print)
ISSN: 1365-294X (online)