English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Mate choice decisions of stickleback females predictably modified by MHC peptide ligands

Milinski, M., Griffiths, S., Wegner, K. M., Reusch, T. B. H., Haas-Assenbaum, A., & Boehm, T. (2005). Mate choice decisions of stickleback females predictably modified by MHC peptide ligands. Proceedings of the National Academy of Sciences of the United States of America, 102(12), 4414-4418. doi:10.1073/pnas.0408264102.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-D9DF-4 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-000F-D9E0-F
Genre: Journal Article

Files

show Files
hide Files
:
milinski_2005.pdf (Publisher version), 312KB
 
File Permalink:
-
Name:
milinski_2005.pdf
Description:
-
Visibility:
Restricted (Max Planck Institute for Evolutionary Biology, Plön; )
MIME-Type / Checksum:
application/pdf
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show

Creators

show
hide
 Creators:
Milinski, Manfred1, Author              
Griffiths, Siân1, Author              
Wegner, K. Mathias1, Author              
Reusch, Thorsten B. H.1, 2, Author              
Haas-Assenbaum, Annette, Author
Boehm, Thomas, Author
Affiliations:
1Department Evolutionary Ecology, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_1445634              
2Department Ecophysiology, Max Planck Institute for Limnology, Max Planck Institute for Evolutionary Biology, Max Planck Society, ou_976547              

Content

show
hide
Free keywords: sexual selection; olfaction; immunogenetics
 Abstract: Sexual selection has been proposed as one mechanism to explain the maintenance of high allelic diversity in MHC genes that control the extent of resistance against pathogens and parasites in natural populations. MHC-based sexual selection is known to involve olfactory mechanisms in fish, mice, and humans. During mate choice, females of the three-spined stickleback (Gasterosteus aculeatus) use an odor-based selection strategy to achieve an optimal level of MHC diversity in their offspring, equipping them with optimal resistance toward pathogens and parasites. The molecular mechanism of odor-based mate-selection strategies is unknown. Because peptide ligands for MHC class I molecules function as individuality signals in mice, we hypothesized that female sticklebacks might assess the degree of MHC diversity of potential partners by means of the structural diversity of the corresponding peptide ligands in perceived odor signals. We show that structurally diverse MIHC ligands interact with natural odors of male sticklebacks to predictably modify MHC-related mate choice. For a mating pair with suboptimal numbers of MHC alleles, peptides increase the attractiveness of male water, whereas for a mating pair with superoptimal numbers, attractiveness is decreased. Our results suggest that female sticklebacks use evolutionarily conserved structural features of MHC peptide ligands to evaluate MHC diversity of their prospective mating partners.

Details

show
hide
Language(s): eng - English
 Dates: 2005-03-22
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: eDoc: 217935
DOI: 10.1073/pnas.0408264102
Other: 2372/S 38350
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Proceedings of the National Academy of Sciences of the United States of America
  Alternative Title : PNAS
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 102 (12) Sequence Number: - Start / End Page: 4414 - 4418 Identifier: ISSN: 0027-8424