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  Gap genes and gradients - The logic behind the gaps

Hülskamp, M., & Tautz, D. (1991). Gap genes and gradients - The logic behind the gaps. Bioessays, 13(6), 261-268. doi:10.1002/bies.950130602.

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Hülskamp, M.1, Autor
Tautz, D.2, Autor           
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1external, ou_persistent22              
2External, ou_persistent22              

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 Zusammenfassung: Gap genes stand at the top of the zygotic segmentation hierarchy in Drosophila. Their expression domains are set up by a combination of maternal regulatory signals and interactions among themselves. In addition, these regulatory pathways are partially redundantly specified by the maternal and zygotic genomes, or by multiple zygotic gene products. The gap genes code for transcription factors which exert their function by forming short-range morphogenetic gradients; differential concentrations of these transcription factors can either act as activators or as repressors for the expression domains of neighbouring genes. It is possible to view the gap genes as a system of genes that subdivides the embryo by forming an activation-repression cascade proceeding from anterior towards posterior.

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 Datum: 1991-061991-06
 Publikationsstatus: Erschienen
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 Ort, Verlag, Ausgabe: -
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 Art der Begutachtung: -
 Identifikatoren: ISI: A1991FT97800001
DOI: 10.1002/bies.950130602
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Titel: Bioessays
  Andere : Bioessays
Genre der Quelle: Zeitschrift
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Ort, Verlag, Ausgabe: Cambridge, UK : Co. of Biologists
Seiten: - Band / Heft: 13 (6) Artikelnummer: - Start- / Endseite: 261 - 268 Identifikator: ISSN: 0265-9247
CoNE: https://pure.mpg.de/cone/journals/resource/954925499109