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  Semiconductor chips with ion channels, nerve cells and brain

Fromherz, P. (2003). Semiconductor chips with ion channels, nerve cells and brain. Physica E-Low-Dimensional Systems & Nanostructures, 16(1), 24-34.

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Genre: Journal Article
Alternative Title : Physica E

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 Creators:
Fromherz, P.1, Author              
Affiliations:
1Fromherz, Peter / Membrane and Neurophysics, Max Planck Institute of Biochemistry, Max Planck Society, ou_1565146              

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Free keywords: silicon; nerve cells; membranes; ion channels
 Abstract: The electrical interfacing of individual nerve cells and semiconductor microstructures as well as the assembly of neuronal networks and microelectronic circuits, is considered. At first the planar core-coat conductor of a neuron-silicon junction is studied as it determines the coupling of ion- conducting neurons and electron-conducting silicon. The width of the cleft between cell and chip, the resistance of cleft and voltage-gate ion channels in the junction are investigated. On that basis, a subsequent section describes the electronic interfacing of individual cultured neurons with silicon microstructurcs as well as the integration of microelectronics with small neuronal networks grown in Culture. In a final part, the electronic interfacing of cultured brain slices is addressed, The goal of this approach is an integration of neuronal network dynamics and digital computation on a microscopic level for studies in brain research, biosensorics, information technology and medical prosthetics. (C) 2002 Elsevier Science B.V. All rights reserved.

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Language(s): eng - English
 Dates: 2003-01
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: eDoc: 41748
ISI: 000180775500006
 Degree: -

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Title: Physica E-Low-Dimensional Systems & Nanostructures
  Alternative Title : Physica E
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 16 (1) Sequence Number: - Start / End Page: 24 - 34 Identifier: ISSN: 1386-9477