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  Proteasome: from structure to function

Stock, D., Nederlof, P. M., Seemüller, E., Baumeister, W., Huber, R., & Löwe, J. (1996). Proteasome: from structure to function. Current Opinion in Biotechnology., 7(4), 376-385.

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Stock, D., Author
Nederlof, P. M., Author
Seemüller, E.1, Author              
Baumeister, W.1, Author              
Huber, R.1, Author              
Löwe, J., Author
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1External Organizations, ou_persistent22              

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Free keywords: Animal; *Cysteine Endopeptidases/ch [Chemistry]; Cysteine Endopeptidases/im [Immunology]; *Cysteine Endopeptidases/ph [Physiology]; Human; Models, Biological; Models, Immunological; Models, Molecular; *Multienzyme Complexes/ch [Chemistry]; Multienzyme Complexes/im [Immunology]; *Multienzyme Complexes/ph [Physiology]; Protein Conformation; Protein Folding
 Abstract: During the past two years, significant progress has been made in understanding the structure and function of the proteasome. Recent work has revealed the three-dimensional structure of the 700 kDa proteolytic complex at atomic resolution and elucidated its novel catalytic mechanism. Close relationships to a number of other amino-terminal hydrolases have emerged, making the proteasomal subunits the prototype of this newly discovered structural superfamily. [References: 75]

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 Dates: 1996
 Publication Status: Published in print
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 Identifiers: eDoc: 318770
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Title: Current Opinion in Biotechnology.
Source Genre: Journal
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Pages: - Volume / Issue: 7 (4) Sequence Number: - Start / End Page: 376 - 385 Identifier: -