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  Has negative staining still a place in biomacromolecular electron microscopy?

Bremer, A., Henn, C., Engel, A., Baumeister, W., & Aebi, U. (1992). Has negative staining still a place in biomacromolecular electron microscopy? Ultramicroscopy., 46(1-4), 85-111.

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Bremer, A., Author
Henn, C., Author
Engel, A., Author
Baumeister, W.1, Author              
Aebi, U., Author
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1External Organizations, ou_persistent22              

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Free keywords: Histocytological Preparation Techniques; *Microscopy, Electron/mt [Methods]; Microscopy, Electron/td [Trends]; *Negative Staining; *Proteins/ul [Ultrastructure]; Support, Non-U.S. Gov't
 Abstract: Transmission electron microscopy of proteins has provided molecular- and in a few cases near-atomic-resolution structural information. In this review, we critically evaluate the potential and the limitations in obtaining molecular resolution, particularly with negatively stained specimens, and put these into perspective with cryomicroscopy of unstained frozen-hydrated and sugar-embedded preparations. [References: 114]

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 Dates: 1992
 Publication Status: Published in print
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 Identifiers: eDoc: 318329
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Title: Ultramicroscopy.
Source Genre: Journal
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Pages: - Volume / Issue: 46 (1-4) Sequence Number: - Start / End Page: 85 - 111 Identifier: -