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  ConsensusPathDB: toward a more complete picture of cell biology

Kamburov, A., Pentchev, K., Galicka, H., Wierling, C., Lehrach, H., & Herwig, R. (2011). ConsensusPathDB: toward a more complete picture of cell biology. Nucleic Acids Research (London), 39(Database issue), D712-D717. doi:10.1093/nar/gkq1156.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-788A-B Version Permalink: http://hdl.handle.net/21.11116/0000-0001-0227-1
Genre: Journal Article

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 Creators:
Kamburov, A.1, Author              
Pentchev, K.2, Author              
Galicka, H.1, Author              
Wierling, C.3, Author              
Lehrach, H.2, Author              
Herwig, R., Author
Affiliations:
1Bioinformatics (Ralf Herwig), Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479648              
2Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433550              
3Systems Biology (Christoph Wierling), Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479656              

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Free keywords: Animals; *Databases, Factual; Databases, Genetic; Gene Expression; *Gene Regulatory Networks; Humans; Internet; *Metabolic Networks and Pathways; Mice; *Protein Interaction Mapping; *Signal Transduction; User-Computer Interface
 Abstract: ConsensusPathDB is a meta-database that integrates different types of functional interactions from heterogeneous interaction data resources. Physical protein interactions, metabolic and signaling reactions and gene regulatory interactions are integrated in a seamless functional association network that simultaneously describes multiple functional aspects of genes, proteins, complexes, metabolites, etc. With 155,432 human, 194,480 yeast and 13,648 mouse complex functional interactions (originating from 18 databases on human and eight databases on yeast and mouse interactions each), ConsensusPathDB currently constitutes the most comprehensive publicly available interaction repository for these species. The Web interface at http://cpdb.molgen.mpg.de offers different ways of utilizing these integrated interaction data, in particular with tools for visualization, analysis and interpretation of high-throughput expression data in the light of functional interactions and biological pathways.

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Language(s): eng - English
 Dates: 2010-11-112011-01
 Publication Status: Published in print
 Pages: 6
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1093/nar/gkq1156
 Degree: -

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Title: Nucleic Acids Research (London)
  Other : Nucleic Acids Res
Source Genre: Journal
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Publ. Info: Oxford : Oxford University Press
Pages: - Volume / Issue: 39 (Database issue) Sequence Number: - Start / End Page: D712 - D717 Identifier: ISSN: 0305-1048
CoNE: https://pure.mpg.de/cone/journals/resource/110992357379342