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  Automation in the high-throughput selection of random combinatorial libraries-different approaches for select applications

Glökler, J., Schütze, T., & Konthur, Z. (2010). Automation in the high-throughput selection of random combinatorial libraries-different approaches for select applications. Molecules, 15(4), 2478-2490. doi:10.3390/molecules15042478.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-7B7D-F Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-7B7E-D
Genre: Journal Article

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Glökler.pdf (Any fulltext), 268KB
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 Creators:
Glökler, J.1, Author              
Schütze, T.1, Author              
Konthur, Z.2, Author              
Affiliations:
1Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433550              
2In vitro Ligand Screening (Zoltán Konthur), Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479653              

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Free keywords: Automation, Laboratory; Combinatorial Chemistry Techniques; High-Throughput Screening Assays; Peptide Library; Robotics; SELEX Aptamer Technique; Small Molecule Libraries/chemistry
 Abstract: Automation in combination with high throughput screening methods has revolutionised molecular biology in the last two decades. Today, many combinatorial libraries as well as several systems for automation are available. Depending on scope, budget and time, a different combination of library and experimental handling might be most effective. In this review we will discuss several concepts of combinatorial libraries and provide information as what to expect from these depending on the given context.

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Language(s): eng - English
 Dates: 2010-04
 Publication Status: Published in print
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 Identifiers: eDoc: 552745
DOI: 10.3390/molecules15042478
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Title: Molecules
Source Genre: Journal
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Pages: - Volume / Issue: 15 (4) Sequence Number: - Start / End Page: 2478 - 2490 Identifier: ISSN: 1420-3049 (Electronic)