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  L1Base: from functional annotation to prediction of active LINE-1 elements

Penzkofer, T., Dandekar, T., & Zemojtel, T. (2005). L1Base: from functional annotation to prediction of active LINE-1 elements. Database Issue, D498-D500. doi:10.1093/nar/gki044.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-8543-F Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-8544-D
Genre: Journal Article
Alternative Title : NAR

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 Creators:
Penzkofer, Tobias, Author
Dandekar, Thomas, Author
Zemojtel, Tomasz1, Author              
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1Dept. of Computational Molecular Biology (Head: Martin Vingron), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433547              

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 Abstract: L1Base is a dedicated database containing putatively active LINE-1 (L1) insertions residing in human and rodent genomes that are as follows: (i) intact in the two open reading frames (ORFs), full-length L1s (FLI-L1s) and (ii) intact ORF2 but disrupted ORF1 (ORF2-L1s). In addition, due to their regulatory potential, the full-length (>6000 bp) non-intact L1s (FLnI-L1s) were also included in the database. Application of a novel annotation methodology, L1Xplorer, allowed in-depth annotation of functional sequence features important for L1 activity, such as transcription factor binding sites and amino acid residues. The L1Base is available online at http://l1base.molgen.mpg.de. In addition, the data stored in the database can be accessed from the Ensembl web browser via a DAS service (http://l1das.molgen.mpg.de:8080/das).

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Language(s): eng - English
 Dates: 2005-12-01
 Publication Status: Published in print
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 Identifiers: eDoc: 268475
DOI: 10.1093/nar/gki044
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Title: Database Issue
Source Genre: Issue
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Pages: - Volume / Issue: - Sequence Number: - Start / End Page: D498 - D500 Identifier: -

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Title: Nucleic Acids Research
  Alternative Title : NAR
Source Genre: Journal
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Pages: - Volume / Issue: 33 Sequence Number: - Start / End Page: - Identifier: ISSN: 0305-1048