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  Finding kinetic parameters using text mining

Hakenberg, J., Schmeier, S., Kowald, A., Klipp, E., & Leser, U. (2004). Finding kinetic parameters using text mining. OMICS: A Journal of Integrative Biology, 8(2), 131-152.

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 Creators:
Hakenberg, Jörg, Author
Schmeier, Sebastian1, Author
Kowald, Axel2, Author              
Klipp, Edda2, Author              
Leser, Ulf, Author
Affiliations:
1Max Planck Society, ou_persistent13              
2Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433554              

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 Abstract: The mathematical modeling and description of complex biological processes has become more and more important over the last years. Systems biology aims at the computational simulation of complex systems, up to whole cell simulations. An essential part focuses on solving a large number of parameterized differential equations. However, measuring those parameters is an expensive task, and finding them in the literature is very laborious. We developed a text mining system that supports researchers in their search for experimentally obtained parameters for kinetic models. Our system classifies full text documents regarding the question whether or not they contain appropriate data using a support vector machine. We evaluated our approach on a manually tagged corpus of 800 documents and found that it outperforms keyword searches in abstracts by a factor of five in terms of precision.

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Language(s): eng - English
 Dates: 2004-07
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 230216
 Degree: -

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Title: OMICS: A Journal of Integrative Biology
Source Genre: Journal
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Pages: - Volume / Issue: 8 (2) Sequence Number: - Start / End Page: 131 - 152 Identifier: ISSN: 1536-2310