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  Proteomic studies using microarrays

Feilner, T., Kreutzberger, J., Niemann, B., Kramer, A., Possling, A., Seitz, H., et al. (2004). Proteomic studies using microarrays. Current Proteomics, 1(4), 283-295.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-892C-7 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-892D-5
Genre: Journal Article

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 Creators:
Feilner, Tanja1, Author              
Kreutzberger, Jürgen1, Author              
Niemann, Birgit, Author
Kramer, Arnim, Author
Possling, Alexandra, Author
Seitz, Harald1, Author              
Kersten, Birgit2, Author
Affiliations:
1Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433550              
2Max Planck Society, ou_persistent13              

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 Abstract: Microarray technology plays an increasing role in proteomic research. We give an overview about recent developments in this technology focusing on molecular interaction studies using protein and antibody microarrays. We report about technical aspects in the development of protein microarrays and describe different surfaces and detection modes. Furthermore, we review the applications of protein microarrays in different molecular interaction studies including interactions of proteins with antibodies, proteins, DNA, small molecules and enzymes. Advantages and limitations of the microarray-based methods with other in vitro methods have been compared. We present the increasing applications of protein and antibody microarrays in basic research, diagnostics, drug discovery, and in vitro-risk assessment of nutrients.

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Language(s): eng - English
 Dates: 2004
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 230191
 Degree: -

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Title: Current Proteomics
Source Genre: Journal
 Creator(s):
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Publ. Info: -
Pages: - Volume / Issue: 1 (4) Sequence Number: - Start / End Page: 283 - 295 Identifier: ISSN: 1570-1646