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  Protein and antibody microarray technology

Glokler, J., & Angenendt, P. (2003). Protein and antibody microarray technology. Interactions in Biological Systems, 229-240. doi:10.1016/j.jchromb.2003.08.034.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-8965-3 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-8966-1
Genre: Journal Article
Alternative Title : J. Chromatogr. B

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 Creators:
Glokler, Joern1, Author              
Angenendt, Philipp1, Author              
Affiliations:
1Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433550              

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Free keywords: review, microarray technologies, proteomics, proteins, antibodies
 Abstract: Following the age of genomics having sequenced the human genome, interest is shifted towards the function of genes. This new age of proteomics brings about a change of methods to study the properties of gene products on a large scale. Protein separation technologies are now applied to allow high-throughput purification and characterisation of proteins. Two-dimensional-gel electrophoresis (2DE) and mass spectrometry (MS) have become widely used tools in the field of proteomics. At the same time, protein and antibody microarrays have been developed as successor of DNA microarrays to soon allow the proteome-wide screening of protein function in parallel. This review is aimed to introduce this new technology and to highlight its current prospects and limitations.

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Language(s): eng - English
 Dates: 2003-11-25
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Degree: -

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Title: Interactions in Biological Systems
Source Genre: Issue
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Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: - Start / End Page: 229 - 240 Identifier: -

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Title: Journal of Chromatography B-Analytical Technologies in the Biomedical and Life Sciences
  Alternative Title : J. Chromatogr. B
Source Genre: Journal
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Publ. Info: -
Pages: - Volume / Issue: 797 (1-2) Sequence Number: - Start / End Page: - Identifier: ISSN: 1570-0232