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  Preferential expression of the G90 gene in post-mitotic cells during mouse embryonic development

Meunier, D., Peters, T., Lüttges, A., Curfs, J., & Fundele, R. (2003). Preferential expression of the G90 gene in post-mitotic cells during mouse embryonic development. Anatomy and Embryology, 207(2), 109-117. doi:10.1007/s00429-003-0330-9.

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Genre: Journal Article
Alternative Title : Anat. Embryol.

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 Creators:
Meunier, Dominique1, Author
Peters, Theo, Author
Lüttges, Angela2, Author              
Curfs, Jo, Author
Fundele, Reinald2, Author              
Affiliations:
1Max Planck Society, ou_persistent13              
2Dept. of Human Molecular Genetics (Head: Hans-Hilger Ropers), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433549              

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Free keywords: inner ear; sensory epithelia; proliferation; differentiation; gene expression
 Abstract: G90 is a novel mouse gene that does not belong to any known gene family. It has previously been shown that this gene is expressed exclusively in post-mitotic cells of the adult mouse intestine and testis, therefore suggesting a role in the control of proliferation and/or differentiation. Here we report the detailed spatio-temporal expression pattern of G90 during mouse embryonic development. We found G90 expression in specific structures of the developing head, namely the brain, inner and middle ear, olfactory epithelium, vomeronasal organ, nasopharynx, oropharynx, papillae of the tongue and oral cavity, pituitary gland and epiglottis. Interestingly, there was a clear correlation between G90 expression and absence of proliferation in most of the cells showing expression of this gene during embryonic development; this finding supported our functional hypothesis.

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Language(s): eng - English
 Dates: 2003-09
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 127763
ISI: 000185394500003
DOI: 10.1007/s00429-003-0330-9
 Degree: -

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Title: Anatomy and Embryology
  Alternative Title : Anat. Embryol.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 207 (2) Sequence Number: - Start / End Page: 109 - 117 Identifier: ISSN: 0340-2061