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  SIR-dependent repression of non-telomeric genes in Saccharomyces cerevisiae?

Marchfelder, U., Rateitschak, K., & Ehrenhofer-Murray, A. E. (2003). SIR-dependent repression of non-telomeric genes in Saccharomyces cerevisiae? Yeast, 20(9), 797-801. doi:10.1002/yea.1001.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-89F1-9 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0010-89F2-7
Genre: Journal Article
Alternative Title : Yeast

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 Creators:
Marchfelder, Uta1, Author              
Rateitschak, Katja2, Author
Ehrenhofer-Murray, Ann E.3, Author              
Affiliations:
1Dept. of Vertebrate Genomics (Head: Hans Lehrach), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433550              
2Max Planck Society, ou_persistent13              
3Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1433554              

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Free keywords: silencing; chromatin; heterochromatin; Saccharomyces cerevisiae
 Abstract: The proteins Sir2, Sir3 and Sir4 repress transcription of the silent mating-type loci HML and HMR and of reporter genes inserted at telomeres. Previous microarray analyses suggested that additional non-telomeric genes exist which are repressed by the Sir proteins. In this study, we tested the expression of 12 such genes by Northern analysis and RT-PCR. However, we were unable to verify their SIR-dependent regulation, which suggests that SIR-mediated repression may be restricted to the known repressed regions.

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Language(s): eng - English
 Dates: 2003-07-15
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: eDoc: 173773
ISI: 000184124100004
DOI: 10.1002/yea.1001
 Degree: -

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Title: Yeast
  Alternative Title : Yeast
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 20 (9) Sequence Number: - Start / End Page: 797 - 801 Identifier: ISSN: 0749-503X