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  Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry

Sauer, S., & Gut, I. G. (2002). Genotyping single-nucleotide polymorphisms by matrix-assisted laser-desorption/ionization time-of-flight mass spectrometry. Journal of Chromatography B, 782(1 - 2), 73-87.

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 Creators:
Sauer, Sascha1, Author              
Gut, Ivo G., Author
Affiliations:
1Nutrigenomics and Gene Regulation (Sascha Sauer), Independent Junior Research Groups (OWL), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479662              

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Free keywords: Reviews; Single-nucleotide polymorphism; Genotyping
 Abstract: In recent years matrix-assisted laser desorption/ionization time-of-flight mass spectrometry (MALDI) has emerged as a very powerful method for genotyping single nucleotide polymorphisms. The accuracy, speed of data accumulation, and data structure are the major features of MALDI. Several SNP genotyping methods have been implemented with a high degree of automation and are being applied for large-scale association studies. Most methods for SNP genotyping using MALDI mass spectrometric detection and their potential application for high-throughput are reviewed here.

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Language(s): eng - English
 Dates: 2002-10-17
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 29181
 Degree: -

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Title: Journal of Chromatography B
Source Genre: Journal
 Creator(s):
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Publ. Info: -
Pages: - Volume / Issue: 782 (1 - 2) Sequence Number: - Start / End Page: 73 - 87 Identifier: -