English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  SpliceNest: visualizing gene structure and alternative splicing based on EST clusters

Coward, E., Haas, S. A., & Vingron, M. (2002). SpliceNest: visualizing gene structure and alternative splicing based on EST clusters. Trends in Genetics, 18(1), 53-55.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Coward, Eivind1, Author
Haas, Stefan A.1, Author
Vingron, Martin2, Author           
Affiliations:
1Max Planck Society, ou_persistent13              
2Gene regulation (Martin Vingron), Dept. of Computational Molecular Biology (Head: Martin Vingron), Max Planck Institute for Molecular Genetics, Max Planck Society, ou_1479639              

Content

show
hide
Free keywords: alternative splicing; expressed sequence tag; gene index; EST; SpliceNest; gene structrue; contig
 Abstract: Messenger RNA sequences, expressed sequence tags (ESTs), and, in particular, consensus sequences of clustered ESTs provide valuable information about splice variants of genes. We have mapped such (predicted) human mRNA sequences onto human genomic DNA to compute gene structure and splice variants. The results of this computation have been collected in a public database, SpliceNest, with a web-based, interactive graphical user interface. The quality of the presented data profits from previous assembly of ESTs and allows for analysis of gene structure and detection of splice variants in conjunction with the clones and libraries that indicated variants. A new, web-accessible database, SpliceNest, contains predicted human gene structure and splice variants derived from human mRNAs and coding sequences predicted from EST assemblies and mapped onto genomic DNA.

Details

show
hide
Language(s): eng - English
 Dates: 2002-01-01
 Publication Status: Issued
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: eDoc: 27794
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Trends in Genetics
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 18 (1) Sequence Number: - Start / End Page: 53 - 55 Identifier: -