English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Functional Specialization of Parallel Motion Detection Circuits in the Fly

Joesch, M., Weber, F., Eichner, H., & Borst, A. (2013). Functional Specialization of Parallel Motion Detection Circuits in the Fly. JOURNAL OF NEUROSCIENCE, 33(3), 902-905. doi:10.1523/JNEUROSCI.3374-12.2013.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000E-B644-C Version Permalink: http://hdl.handle.net/11858/00-001M-0000-000E-B646-8
Genre: Journal Article

Files

show Files
hide Files
:
902.full.pdf (Any fulltext), 376KB
Name:
902.full.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
open access article
License:
-

Locators

show

Creators

show
hide
 Creators:
Joesch, Maximilian1, Author              
Weber, Franz1, Author              
Eichner, Hubert1, Author              
Borst, Alexander1, Author              
Affiliations:
1Department: Systems and Computational Neurobiology / Borst, MPI of Neurobiology, Max Planck Society, ou_1113548              

Content

show
hide
Free keywords: DROSOPHILA-MELANOGASTER; VISUAL INTERNEURONS; PATHWAYS; VISION; MEDULLA; SYSTEM
 Abstract: In the fly Drosophila melanogaster, photoreceptor input to motion vision is split into two parallel pathways as represented by first-order interneurons L1 and L2 (Rister et al., 2007; Joesch et al., 2010). However, how these pathways are functionally specialized remains controversial. One study (Eichner et al., 2011) proposed that the L1-pathway evaluates only sequences of brightness increments (ON-ON), while the L2-pathway processes exclusively brightness decrements (OFF-OFF). Another study (Clark et al., 2011) proposed that each of the two pathways evaluates both ON-ON and OFF-OFF sequences. To decide between these alternatives, we recorded from motion-sensitive neurons in flies in which the output from either L1 or L2 was genetically blocked. We found that blocking L1 abolishes ON-ON responses but leaves OFF-OFF responses intact. The opposite was true, when the output from L2 was blocked. We conclude that the L1 and L2 pathways are functionally specialized to detect ON-ON and OFF-OFF sequences, respectively.

Details

show
hide
Language(s): eng - English
 Dates: 2013-01-16
 Publication Status: Published in print
 Pages: 4
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: JOURNAL OF NEUROSCIENCE
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: 11 DUPONT CIRCLE, NW, STE 500, WASHINGTON, DC 20036 USA : SOC NEUROSCIENCE
Pages: - Volume / Issue: 33 (3) Sequence Number: - Start / End Page: 902 - 905 Identifier: ISSN: 0270-6474