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  Diagnostic imaging in obesity

Machann, J., Horstmann, A., Born, M., Hesse, S., & Hirsch, F. W. (2013). Diagnostic imaging in obesity. Best Practice and Research. Clinical Endocrinology and Metabolism, 27(2), 261-277. doi:10.1016/j.beem.2013.02.003.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000E-BAC9-2 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-84A3-F
Genre: Journal Article

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 Creators:
Machann, Jürgen1, 2, Author
Horstmann, Annette3, 4, Author              
Born, Mark5, Author
Hesse, Swen4, 6, Author
Hirsch, Franz Wolfgang7, Author
Affiliations:
1Institute for Diabetes Research and Metabolic Diseases (IDM) of the Helmholtz Center Munich, Eberhard Karls University Tübingen, Germany, ou_persistent22              
2Section on Experimental Radiology, Department of Diagnostic and Interventional Radiology, University Hospital Tübingen, Germany, ou_persistent22              
3Department Neurology, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634549              
4Integrated Research and Treatment Center Adiposity Diseases, University of Leipzig, Germany, ou_persistent22              
5Paediatric Radiology, Department of Radiology, University Bonn, Germany, ou_persistent22              
6Department of Nuclear Medicine, University of Leipzig, Germany, ou_persistent22              
7Department of Pediatric Radiology, University Hospital Leipzig, Germany, ou_persistent22              

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Free keywords: Imaging; MRI; Ultrasound; Nuclear medicine; Obesity; Spectroscopy; Functional MR; Radiotracer
 Abstract: Magnetic resonance of the body offers different techniques for mapping fat deposits (MR Imaging) and analysis of organs with small amounts of lipids (MR Spectroscopy). Possible approaches for whole-body assessment of adipose tissue are presented and discussed and spectroscopic examinations in different organs are depicted. With magnetic resonance imaging (MRI) it has been shown that obesity per se is not a marker for metabolic failure, but depends on regional variations of body composition and ectopic lipid accumulation. In addition MRI of the brain is a powerful research tool to understand the brain’s role in the development and maintenance of obesity and the overconsumption of foods in obese individuals. Sonography has a low accuracy in estimating hepatic steatosis until now. New sonographic methods have been evaluated to detect hepatic steatosis by physical properties of fatty tissue as tissue stiffness, sound absorption or sound speed. Nuclear medicine and in particular PET methods are used to explore central pathophysiology, brown adipose tissue activity and alterations in homeostatic feedback and gut-brain communication.

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Language(s): eng - English
 Dates: 2013-02-142013-03-052013-04
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1016/j.beem.2013.02.003
PMID: 23731887
Other: Epub 2013
 Degree: -

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Title: Best Practice and Research. Clinical Endocrinology and Metabolism
  Abbreviation : Best Pract. Res. Clin. Endocrinol. Metab.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Amsterdam, NL : Harcourt Publishers
Pages: - Volume / Issue: 27 (2) Sequence Number: - Start / End Page: 261 - 277 Identifier: ISSN: 1521-690X
CoNE: https://pure.mpg.de/cone/journals/resource/1521-690X