English
 
Help Privacy Policy Disclaimer
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Direct Room-Temperature Lactonisation of Alcohols and Ethers onto Amides: an “Amide Strategy” for Synthesis

Valerio, V., Petkova, D., Madelaine, C., & Maulide, N. (2013). Direct Room-Temperature Lactonisation of Alcohols and Ethers onto Amides: an “Amide Strategy” for Synthesis. Chemistry-a European Journal, 19(8), 2606-2610. doi:10.1002/chem.201203906.

Item is

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Valerio, Viviana1, Author              
Petkova, Desislava1, Author              
Madelaine, Claire1, Author              
Maulide, Nuno1, Author              
Affiliations:
1Research Group Maulide, Max-Planck-Institut für Kohlenforschung, Max Planck Society, ou_1445614              

Content

show
hide
Free keywords: amides; electrophilic activation; lactones; mechanistic studies; triflic anhydrides
 Abstract: Last-minute deal: A direct lactonisation of ethers and alcohols onto amides that proceeds at room temperature under mild conditions is reported (see scheme). This allows the effective saving of up to two unproductive, sequential deprotection operations in synthetic sequences. Mechanistic studies are described, and a new “amide strategy” that exploits the dual robustness/late-stage selective activation properties of this functional group is outlined.

Details

show
hide
Language(s): eng - English
 Dates: 2013-01-102013-02-18
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1002/chem.201203906
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Chemistry-a European Journal
  Other : Chem.-Eur. J.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 19 (8) Sequence Number: - Start / End Page: 2606 - 2610 Identifier: ISSN: 0947-6539
CoNE: https://pure.mpg.de/cone/journals/resource/954926979058