ausblenden:
Schlagwörter:
homogeneous catalysis; oxidative coupling; quinolines; vanadium
Zusammenfassung:
In the THIQ of it:N-Alkyl tetrahydroisoquinolines are oxidatively coupled with a variety of nucleophiles in the presence of m-CPBA and [VO(acac)2]. This method has been applied to the synthesis of the opioid methopholine.