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  Slice accelerated diffusion-weighted imaging at ultra-high field strength

Eichner, C., Setsompop, K., Koopmans, P. J., Lützkendorf, R., Norris, D. G., Turner, R., et al. (2014). Slice accelerated diffusion-weighted imaging at ultra-high field strength. Magnetic Resonance in Medicine, 71(4), 1518-1525. doi:10.1002/mrm.24809.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-000E-FB0B-1 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-8392-3
Genre: Journal Article

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 Creators:
Eichner, Cornelius1, 2, 3, Author              
Setsompop, Kawim2, 3, Author
Koopmans, Peter J.4, Author
Lützkendorf, Ralf5, Author
Norris, David G.6, Author
Turner, Robert1, Author              
Wald, Lawrence L.2, 3, Author
Heidemann, Robin M.1, 7, Author              
Affiliations:
1Department Neurophysics, MPI for Human Cognitive and Brain Sciences, Max Planck Society, ou_634550              
2Athinoula A. Martinos Center for Biomedical Imaging, Charlestown, MA, USA, ou_persistent22              
3Harvard Medical School, Harvard University, Boston, MA, USA, ou_persistent22              
4FMRIB Centre, University of Oxford, United Kingdom, ou_persistent22              
5Otto von Guericke University Magdeburg, Germany, ou_persistent22              
6Donders Institute for Brain, Cognition and Behaviour, Radboud University, Nijmegen, the Netherlands, ou_persistent22              
7Siemens Sector Healthcare, Erlangen, Germany, ou_persistent22              

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Free keywords: CAIPIRINHA; Simultaneous multislice; Diffusion MRI; Ultra-high field; PINS pulse
 Abstract: Purpose Diffusion magnetic resonance imaging (dMRI) data with very high isotropic resolution can be obtained at 7T. However, for extensive brain coverage, a large number of slices is required, resulting in long acquisition times (TAs). Recording multiple slices simultaneously (SMS) promises to reduce the TA. Methods A combination of zoomed and parallel imaging is used to achieve high isotropic resolution dMRI data with a low level of distortions at 7T. The blipped-CAIPI (controlled aliasing in parallel imaging) approach is used to acquire several slices simultaneously. Due to their high radiofrequency (RF) power deposition and ensuing specific absorption rate (SAR) constraints, the commonly used multiband (MB) RF pulses for SMS imaging are inefficient at 7T and entail long repetition times, counteracting the usefulness of SMS acquisitions. To address this issue, low SAR multislice Power Independent of Number of Slices RF pulses are employed. Results In vivo dMRI results with and without SMS acceleration are presented at different isotropic spatial resolutions at ultra high field strength. The datasets are recorded at a high angular resolution to detect fiber crossings. Conclusion From the results and compared with earlier studies at these resolutions, it can be seen that scan time is significantly reduced, while image quality is preserved.

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Language(s): eng - English
 Dates: 2013-04-232013-06-242014-04
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: Peer
 Identifiers: DOI: 10.1002/mrm.24809
PMID: 23798017
Other: Epub 2013
 Degree: -

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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Pages: - Volume / Issue: 71 (4) Sequence Number: - Start / End Page: 1518 - 1525 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149