English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology?

Carrondo, M. J. T., Alves, P. M., Carinhas, N., Glassey, J., Hesse, F., Merten, O.-W., et al. (2012). How can measurement, monitoring, modeling and control advance cell culture in industrial biotechnology? Biotechnology Journal, 7(12), 1522-1529. doi:10.1002/biot.201200226.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-8A58-4 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-A70E-D
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Carrondo, Manuel J. T.1, 2, Author
Alves, Paula M.1, 2, Author
Carinhas, Nuno1, 2, Author
Glassey, Jarka3, Author
Hesse, Friedemann4, Author
Merten, Otto-Wilhelm5, Author
Micheletti, Martina6, Author
Noll, Thomas7, Author
Oliveira, Rui1, 8, Author
Reichl, Udo9, 10, Author              
Staby, Arne11, Author
Teixeira, Ana P1, 2, Author
Weichert, Henry12, Author
Mandenius, Carl-Fredrik1, Author
Affiliations:
1Instituto de Biologia Experimental e Tecnológica (IBET), Oeiras, Portugal, ou_persistent22              
2Instituto de Tecnologia Química e Bioquímica (ITQB), Universidade Nova de Lisboa, Oeiras, Portugal, ou_persistent22              
3Newcastle University, Newcastle upon Tyne, UK, ou_persistent22              
4University of Applied Sciences, Biberach, Germany, ou_persistent22              
5Généthon, Evry, France, ou_persistent22              
6University College London, London, UK, ou_persistent22              
7University of Bielefeld, Bielefeld, Germany, ou_persistent22              
8Faculdade de Ciˆncias e Tecnologia, Universidade Nova de Lisboa, Caparica, Portugal, ou_persistent22              
9Otto-von-Guericke-Universität Magdeburg, ou_1738156              
10Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738140              
11Novo Nordisk A/S, Gentofte, Denmark and Lund University, Lund, Sweden, ou_persistent22              
12Sartorius Stedim Biotech GmbH, Göttingen, Germany, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: This report highlights the potential of measurement, monitoring, modeling and control (M(3) C) methodologies in animal and human cell culture technology. In particular, state-of-the-art of M(3) C technologies and their industrial relevance of existing technology are addressed. It is a summary of an expert panel discussion between biotechnologists and biochemical engineers with both academic and industrial backgrounds. The latest ascents in M(3) C are discussed from a cell culture perspective for industrial process development and production needs. The report concludes with a set of recommendations for targeting M(3) C research toward the industrial interests. These include issues of importance for biotherapeutics production, miniaturization of measurement techniques and modeling methods. Copyright © 1999–2013 John Wiley & Sons, Inc. All Rights Reserved. [accessed January 10th 2013]

Details

show
hide
Language(s): eng - English
 Dates: 2012
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: eDoc: 626292
DOI: 10.1002/biot.201200226
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Biotechnology Journal
  Other :
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: 7 (12) Sequence Number: - Start / End Page: 1522 - 1529 Identifier: -