English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Brownian diffusion of ion channels in different membrane patch geometries

Wei, F., Yang, D., Straube, R., & Shuai, J. (2011). Brownian diffusion of ion channels in different membrane patch geometries. Physical review E, 83(2), 021919. doi:10.1103/PhysRevE.83.021919.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-8CFA-8 Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0014-533B-0
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Wei, F.1, Author
Yang, D.1, Author
Straube, R.2, Author              
Shuai, J.1, Author
Affiliations:
1Xiamen UniversityDepartment of Physics - Inst. of Theoretical PhysicsChina, ou_persistent22              
2Analysis and Redesign of Biological Networks, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738139              

Content

show
hide
Free keywords: -
 Abstract: We asymptotically calculate the spatially averaged mean first passage time (MFPT) of a diffusing channel protein in a finite membrane patch containing a small absorbing anchor site. Different two-dimensional membrane geometries are considered including a circular, a square-shaped, a rectangular, and a cylindrical domain. The asymptotic expressions are found to be in excellent agreement with results from Monte Carlo simulations if the radius of the diffusing protein is sufficiently small. For a larger radius, a simple correction to the asymptotic expressions is proposed. We show that the average MFPT for a circle and a square-shaped domain of the same area are approximately equal as long as the anchor site is close to the center of the domain. We also discuss how the average MFPT depends on the aspect ratio of a rectangular and a cylindrical domain. Among such domains with a fixed area, a minimal MFPT is obtained for the square-shaped domain. ©2011 American Physical Society [accessed 2013 July 2nd]

Details

show
hide
Language(s): eng - English
 Dates: 2011
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: Peer
 Identifiers: eDoc: 557109
Other: 6/11
DOI: 10.1103/PhysRevE.83.021919
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Physical review E
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Melville, NY : Published by the American Physical Society through the American Institute of Physics
Pages: - Volume / Issue: 83 (2) Sequence Number: - Start / End Page: 021919 Identifier: ISSN: 1539-3755
CoNE: https://pure.mpg.de/cone/journals/resource/954925225012