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  Design of simulated moving bed processes under reduced purity requirements

Kaspereit, M., Seidel-Morgenstern, A., & Kienle, A. (2007). Design of simulated moving bed processes under reduced purity requirements. Journal of Chromatography A, 1162, 2-13. doi:10.1016/j.chroma.2007.02.063.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-98C4-E Version Permalink: http://hdl.handle.net/11858/00-001M-0000-0019-8D4C-9
Genre: Journal Article
Alternative Title : J. Chromatogr. A

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 Creators:
Kaspereit, M.1, Author              
Seidel-Morgenstern, A.2, 3, Author              
Kienle, A.1, 3, Author              
Affiliations:
1Process Synthesis and Process Dynamics, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738153              
2Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738150              
3Otto-von-Guericke-Universität Magdeburg, External Organizations, ou_1738156              

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 Abstract: The design of simulated moving bed chromatography under limited purity requirements is investigated. A parametric study indicates that all internal flow rates should be considered as free parameters in process design. This is confirmed by systematic numerical optimisations of two different design scenarios. A restrictive scenario requires complete regeneration of liquid and solid phases. In contrast, in a non-restrictive design all flow rates are optimised. The latter leads to significantly improved process performance. On the basis of the obtained observations, a simple design method for simulated moving bed processes with desired outlet purity values is derived from equilibrium theory. Copyright © 2007 Elsevier Ltd. All rights reserved. [accessed 2013 November 26th]

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Language(s): eng - English
 Dates: 2007
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: -
 Identifiers: eDoc: 298163
Other: 14/07
DOI: 10.1016/j.chroma.2007.02.063
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Title: Journal of Chromatography A
Source Genre: Journal
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Publ. Info: Amsterdam : Elsevier
Pages: - Volume / Issue: 1162 Sequence Number: - Start / End Page: 2 - 13 Identifier: ISSN: 0021-9673
CoNE: https://pure.mpg.de/cone/journals/resource/954925527837_1