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  Characterization and analytical issues on an influenza A virus production process

Genzel, Y., Kalbfuss, B., Ritter, J. B., Schulze-Horsel, J., Rapp, E., Vester, D., et al. (2006). Characterization and analytical issues on an influenza A virus production process. Talk presented at Vaccines: Quality control, scale-up and manufacture. Hamburg, Germany. 2006-12-05 - 2006-12-06.

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Datensatz-Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-9961-6 Versions-Permalink: http://hdl.handle.net/11858/00-001M-0000-0025-0C7A-5
Genre: Vortrag

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 Urheber:
Genzel, Y.1, Autor              
Kalbfuss, B.1, Autor              
Ritter, J. B.1, Autor              
Schulze-Horsel, J.1, Autor              
Rapp, E.2, Autor              
Vester, D.1, Autor              
Reichl, U.1, 3, Autor              
Affiliations:
1Bioprocess Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738140              
2Physical and Chemical Foundations of Process Engineering, Max Planck Institute for Dynamics of Complex Technical Systems, Max Planck Society, ou_1738150              
3Otto-von-Guericke-Universität Magdeburg, ou_1738156              

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Schlagwörter: -
 Zusammenfassung: Different approaches for a mammalian cell culture based production process for influenza vaccines are currently in development. Each approach needs optimization based on analytical data collected from many small scale experiments. In the presentation results for different cultivation methods (rollerbottles, stirred tank or wave bioreactor microcarrier system) for a production process with adherent MDCK cells are discussed. Analytical data on cell numbers, metabolism, host cell protein level, cell cycle and virus titer are shown.

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Sprache(n): eng - Englisch
 Datum: 2006
 Publikationsstatus: Keine Angabe
 Seiten: -
 Ort, Verlag, Ausgabe: -
 Inhaltsverzeichnis: -
 Art der Begutachtung: -
 Identifikatoren: eDoc: 293565
 Art des Abschluß: -

Veranstaltung

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Titel: Vaccines : Quality control, scale-up and manufacture
Veranstaltungsort: Hamburg, Germany
Start-/Enddatum: 2006-12-05 - 2006-12-06
Eingeladen: Ja

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