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  MR-based field-of-view extension in MR/PET: B0 homogenization using gradient enhancement (HUGE)

Blumhagen, J., Ladebeck, R., Fenchel, M., & Scheffler, K. (2013). MR-based field-of-view extension in MR/PET: B0 homogenization using gradient enhancement (HUGE). Magnetic Resonance in Medicine, 70(4), 1047-1057. doi:10.1002/mrm.24555.

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資料種別: 学術論文

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 作成者:
Blumhagen, JO, 著者
Ladebeck, R, 著者
Fenchel, M, 著者
Scheffler, K1, 2, 著者           
所属:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 要旨: In whole-body MR/PET, the human attenuation correction can be based on the MR data. However, an MR-based field-of-view (FoV) is limited due to physical restrictions such as B0 inhomogeneities and gradient nonlinearities. Therefore, for large patients, the MR image and the attenuation map might be truncated and the attenuation correction might be biased. The aim of this work is to explore extending the MR FoV through B0 homogenization using gradient enhancement in which an optimal readout gradient field is determined to locally compensate B0 inhomogeneities and gradient nonlinearities. A spin-echo-based sequence was developed that computes an optimal gradient for certain regions of interest, for example, the patient's arms. A significant distortion reduction was achieved outside the normal MR-based FoV. This FoV extension was achieved without any hardware modifications. In-plane distortions in a transaxially extended FoV of up to 600 mm were analyzed in phantom studies. In vivo measurements of the patient's arms lying outside the normal specified FoV were compared with and without the use of B0 homogenization using gradient enhancement. In summary, we designed a sequence that provides data for reducing the image distortions due to B0 inhomogeneities and gradient nonlinearities and used the data to extend the MR FoV.

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 日付: 2012-112013-10
 出版の状態: 出版
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 識別子(DOI, ISBNなど): DOI: 10.1002/mrm.24555
BibTex参照ID: BlumhagenLFS2012
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出版物名: Magnetic Resonance in Medicine
種別: 学術雑誌
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出版社, 出版地: -
ページ: - 巻号: 70 (4) 通巻号: - 開始・終了ページ: 1047 - 1057 識別子(ISBN, ISSN, DOIなど): -