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  Synthesis of Some Cyclic Methylene 1,3-Diaza Barbiturates Derivatives

Sweidan, K., Engelmann, J., Joshi, R., Mubarak, M., & El-Abadelah, M. (2011). Synthesis of Some Cyclic Methylene 1,3-Diaza Barbiturates Derivatives. Letters in Organic Chemistry, 8(8), 603-605. doi:10.2174/157017811797249353.

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Item Permalink: https://hdl.handle.net/11858/00-001M-0000-0013-B98C-4 Version Permalink: https://hdl.handle.net/21.11116/0000-0001-B02E-5
Genre: Journal Article

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http://www.eurekaselect.com/88762/article (Publisher version)
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 Creators:
Sweidan, K1, 2, Author           
Engelmann, J1, 2, Author           
Joshi, R1, 2, Author           
Mubarak, MS, Author
El-Abadelah, MM, Author
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: The reaction of 1,3-dimethyl-5-bis(thioethyl)methylene barbituric acid (2) with various vic-diamines leads to the formation of the respective 1,3-diazamethylene barbiturate derivatives 3 (a-f) in high yields. Solid-state 13C-NMR, MS and IR spectral data were employed for the characterization of these compounds. Antimicrobial screening revealed that none of the newly synthesized compounds showed appreciable antibacterial activity.

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 Dates: 2011-10
 Publication Status: Issued
 Pages: -
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 Table of Contents: -
 Rev. Type: -
 Identifiers: DOI: 10.2174/157017811797249353
BibTex Citekey: SweidanEME2011
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Title: Letters in Organic Chemistry
  Other : Lett. Org. Chem.
Source Genre: Journal
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Publ. Info: Saif Zone, Sharjah, U.A.E. : Bentham Science Publishers
Pages: - Volume / Issue: 8 (8) Sequence Number: - Start / End Page: 603 - 605 Identifier: ISSN: 1570-1786
CoNE: https://pure.mpg.de/cone/journals/resource/111078171126014