English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Measurement of CMRO2 changes by somatosensory stimulation in rat using oxygen-17 at 16.4 T

Wiesner, H., Pohmann, R., Balla, D., Chen, W., Ugurbil, K., & Uludag, K. (2011). Measurement of CMRO2 changes by somatosensory stimulation in rat using oxygen-17 at 16.4 T. Poster presented at 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011), Montréal, Canada.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-BC04-9 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-4C27-E
Genre: Poster

Files

show Files
hide Files
:
ISMRM-2011-Wiesner.pdf (Abstract), 166KB
Name:
ISMRM-2011-Wiesner.pdf
Description:
-
Visibility:
Public
MIME-Type / Checksum:
application/pdf / [MD5]
Technical Metadata:
Copyright Date:
-
Copyright Info:
-
License:
-

Locators

show
hide
Locator:
https://www.ismrm.org/11/ (Table of contents)
Description:
-

Creators

show
hide
 Creators:
Wiesner, HM1, 2, Author              
Pohmann, R1, 2, Author              
Balla, DZ1, 2, Author              
Chen, W, Author
Ugurbil, K, Author
Uludag, K1, 2, Author              
Affiliations:
1Department High-Field Magnetic Resonance, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497796              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

Content

show
hide
Free keywords: -
 Abstract: We have observed the first directly measured CMRO2 changes in rats by peripheral somatosensory stimulation at an ultrahigh field strength of 16.4 Tesla. The results show that apart from the high sensitivity required also the stability of baseline metabolism is crucial in detecting small CMRO2 changes evoked by increased neural activity. Lower global baseline metabolism was found when ventilating with a N2O vs. N2 mixture of equal O2 fraction due to the increased anesthetic effect of N2O in agreement with previous work. The direct detection of changes in CMRO2 can also help to investigate the metabolic changes in negative BOLD activations on the ipsilateral hemisphere. Our results are also in accordance with previous results using 17O for CMRO2 measurements from other species at 9.4T.

Details

show
hide
Language(s):
 Dates: 2011-05
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: BibTex Citekey: 7091
 Degree: -

Event

show
hide
Title: 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011)
Place of Event: Montréal, Canada
Start-/End Date: 2011-05-07 - 2011-05-13

Legal Case

show

Project information

show

Source 1

show
hide
Title: 19th Annual Meeting and Exhibition of the International Society for Magnetic Resonance in Medicine (ISMRM 2011)
Source Genre: Proceedings
 Creator(s):
Affiliations:
Publ. Info: -
Pages: - Volume / Issue: - Sequence Number: 5868 Start / End Page: 1482 Identifier: -