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  Electroconvulsive therapy resolves cortical inhibition and manneristic omissions in a chronic catatonic patient

Dresler, T., Giani, A., Reinsberger, C., Scheuerpflug, P., Stöber, G., & Fallgatter, A. (2010). Electroconvulsive therapy resolves cortical inhibition and manneristic omissions in a chronic catatonic patient. Journal of Neural Transmission, 117(10), 1209-1212. doi:10.1007/s00702-010-0467-7.

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 Creators:
Dresler, T, Author
Giani, AS1, 2, 3, Author           
Reinsberger, C, Author
Scheuerpflug, P, Author
Stöber, G, Author
Fallgatter, AJ, Author
Affiliations:
1Research Group Cognitive Neuroimaging, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497804              
2Department Human Perception, Cognition and Action, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497797              
3Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: We investigated a patient with severe catatonic schizophrenia (manneristic catatonia according to Karl Leonhard) treated with electroconvulsive therapy (ECT) after pharmacological approaches did not result in any clinical improvement. Before and after nine ECT sessions a double-pulse transcranial magnetic stimulation (TMS) paradigm was used to measure intracortical inhibition (ICI) which has been shown to be reduced in a significant proportion of patients with schizophrenia. Although the patient showed no remission regarding some psychomotor aspects after ECT, we found an increase in ICI and a remarkable clinical improvement of catatonic omissions which might be due to changes in the GABAergic system.

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 Dates: 2010-10
 Publication Status: Issued
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 Rev. Type: -
 Identifiers: DOI: 10.1007/s00702-010-0467-7
BibTex Citekey: DreslerGRSSF2010
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Title: Journal of Neural Transmission
  Other : J. Neural Transm.
Source Genre: Journal
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Publ. Info: Wien : Springer-Verlag.
Pages: - Volume / Issue: 117 (10) Sequence Number: - Start / End Page: 1209 - 1212 Identifier: ISSN: 0300-9564
CoNE: https://pure.mpg.de/cone/journals/resource/991042725899232