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  Functional MRI in the rat at 9.4 T and 16.4 T

Balla, D., Wiesner, H., Shajan, G., & Pohmann, R. (2010). Functional MRI in the rat at 9.4 T and 16.4 T. Poster presented at ISMRM-ESMRMB Joint Annual Meeting 2010, Stockholm, Sweden.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-C076-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-A510-1
Genre: Poster

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 Creators:
Balla, DZ1, 2, Author              
Wiesner, HM1, 2, Author              
Shajan, G1, 2, Author              
Pohmann, R1, 2, Author              
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Functional MRI (fMRI) in animals at high magnetic fields keeps expanding our knowledge about the basics of neural processing but the specificity of the fMRI-signal is still under ongoing investigation. Yet, as the signal to noise ratio in MRI depends linearly on the magnetic field strength and calls for even stronger magnets for the detection of even smaller anatomical details, the relation between the functional MR-response and field strength can only be approximated with complex models. In this study the blood oxygenation dependent (BOLD) effect was measured and compared at 9.4 T and 16.4 T in the same animal with segmented gradient-echo (GE) and spin-echo (SE) echo planar imaging (EPI) sequence using optimal echo times for the respective field. Furthermore, high resolution fMRI acquisition at 16.4 T was performed up to a 50 µm in-plane accuracy and for an 8 s temporal resolution without the use of cryo-coils or coil-arrays.

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 Dates: 2010-05
 Publication Status: Published in print
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 Identifiers: BibTex Citekey: 7017
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Title: ISMRM-ESMRMB Joint Annual Meeting 2010
Place of Event: Stockholm, Sweden
Start-/End Date: 2010-05-01 - 2010-05-07

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Title: ISMRM-ESMRMB Joint Annual Meeting 2010
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 1216 Start / End Page: - Identifier: -