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  Theoretical and Experimental Evaluation of Continuous Arterial Spin Labeling Techniques

Pohmann, R., Budde, J., Auerbach, E., Adriany, G., & Ugurbil, K. (2010). Theoretical and Experimental Evaluation of Continuous Arterial Spin Labeling Techniques. Magnetic Resonance in Medicine, 63(2), 438-446. doi:10.1002/mrm.22243.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-C144-7 Version Permalink: http://hdl.handle.net/21.11116/0000-0002-7768-4
Genre: Journal Article

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Pohmann, R1, 2, Author              
Budde, J1, 2, Author              
Auerbach , EJ, Author
Adriany, G, Author
Ugurbil, K, Author
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Continuous arterial spin labeling (CASL) is known to be the most sensitive ASL technique. To avoid magnetization transfer effects and to overcome hardware limitations, several sequences have been proposed that adiabatically label the inflowing blood. Four of these methods are examined with respect to their sensitivity both theoretically by Bloch equation simulations and experimentally. All sequences were optimized carefully by adjusting their measurement parameters based exclusively on the results of simulations. Perfusion measurements on the human brain obtained at 3 T result in excellent images from all techniques while differences in sensitivity are similar to those expected from the simulations.

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 Dates: 2010-02
 Publication Status: Published in print
 Pages: -
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 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1002/mrm.22243
BibTex Citekey: 6078
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Title: Magnetic Resonance in Medicine
Source Genre: Journal
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Publ. Info: New York : Wiley-Liss
Pages: - Volume / Issue: 63 (2) Sequence Number: - Start / End Page: 438 - 446 Identifier: ISSN: 0740-3194
CoNE: https://pure.mpg.de/cone/journals/resource/954925538149