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  Semi-supervised Kernel Canonical Correlation Analysis of Human Functional Magnetic Resonance Imaging Data

Shelton, J. (2009). Semi-supervised Kernel Canonical Correlation Analysis of Human Functional Magnetic Resonance Imaging Data. Talk presented at Women in Machine Learning Workshop (WiML 2009). Vancouver, BC, Canada. 2009-12-07.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-C1F0-1 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-1E13-7
Genre: Talk

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 Creators:
Shelton, JA1, 2, Author              
Affiliations:
1Department Empirical Inference, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497795              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: Kernel Canonical Correlation Analysis (KCCA) is a general technique for subspace learning that incorporates principal components analysis (PCA) and Fisher linear discriminant analysis (LDA) as special cases. By finding directions that maximize correlation, KCCA learns representations tied more closely to underlying process generating the the data and can ignore high-variance noise directions. However, for data where acquisition in a given modality is expensive or otherwise limited, KCCA may suffer from small sample effects. We propose to use semi-supervised Laplacian regularization to utilize data that are present in only one modality. This manifold learning approach is able to find highly correlated directions that also lie along the data manifold, resulting in a more robust estimate of correlated subspaces. Functional magnetic resonance imaging (fMRI) acquired data are naturally amenable to subspace techniques as data are well aligned and such data of the human brain are a particularly interesting candidate. In this study we implemented various supervised and semi-supervised versions of KCCA on human fMRI data, with regression to single and multivariate labels (corresponding to video content subjects viewed during the image acquisition). In each variate condition, Laplacian regularization improved performance whereas the semi-supervised variants of KCCA yielded the best performance. We additionally analyze the weights learned by the regression in order to infer brain regions that are important during different types of visual processing.

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 Dates: 2009-12
 Publication Status: Published online
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Type: -
 Identifiers: BibTex Citekey: 6243
 Degree: -

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Title: Women in Machine Learning Workshop (WiML 2009)
Place of Event: Vancouver, BC, Canada
Start-/End Date: 2009-12-07
Invited: Yes

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