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  Calibrating the BOLD signal revisited: Calculation of oxygen metabolism for gradient- and spin-echo sequence up to 16.4T

Uludag, K., Zappe, A.-C., Goense, J., & Logothetis, N. (2009). Calibrating the BOLD signal revisited: Calculation of oxygen metabolism for gradient- and spin-echo sequence up to 16.4T. Poster presented at 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009), Honolulu, HI, USA.

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Uludag, K1, 2, Author           
Zappe, A-C2, 3, Author           
Goense, J2, 3, Author           
Logothetis, NK2, 3, Author           
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              
3Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              

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 Abstract: A BOLD signal model as a function oxygen extraction fraction and CBV was developed in order to determine change in oxidative metabolism from combined BOLD signal and CBF measurements. The new model is an alternative model to the widely used calibrated BOLD approach initally proposed by Davis and colleagues for GRE at 1.5T. The new model, however, takes also intra-vascular MRI signal into account and is developed for both GRE and SE from 1.5T up to 16.4T. In the current study, at 4.7T and 7T using SE and GRE, oxidative metabolism change during visual stimulation was determined in macaque monkeys.

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 Dates: 2009-04
 Publication Status: Published online
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 Identifiers: BibTex Citekey: UludagZGL2009
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Title: 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009)
Place of Event: Honolulu, HI, USA
Start-/End Date: 2009-04-18 - 2009-04-24

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Title: 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3701 Start / End Page: - Identifier: -