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  Highly Accurate Quantification of Proton MR Spectroscopy in Rat Brain in Vivo at 16.4 T

Hong, S.-T., Balla, D., Shajan, G., Ugurbil, K., & Pohmann, R. (2009). Highly Accurate Quantification of Proton MR Spectroscopy in Rat Brain in Vivo at 16.4 T. Poster presented at 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009), Honolulu, HI, USA.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-C563-0 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-1592-0
Genre: Poster

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 Creators:
Hong, S-T1, 2, Author              
Balla, DZ1, 2, Author              
Shajan, G1, 2, Author              
Ugurbil, K, Author
Pohmann, R1, 2, Author              
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: In the present study, we used a 16.4 T scanner to evaluate the quantification of metabolites from the rat brain with an ultra-short TE STEAM sequence. All metabolite resonances, previously observed in vivo and published in the literature, were detected. Additionally, a newly discernible Histidine peaks at 3.11 ppm, 3.22 ppm and 3.97 ppm were detected and quantified for the first time in vivo, with CRLB of below 20 , indicating high quantification reliability. These preliminary results demonstrate the feasibility of detecting new metabolites in combination with the advantages of a high magnetic field strength.

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 Dates: 2009-04
 Publication Status: Published online
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 Identifiers: BibTex Citekey: 5758
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Title: 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009)
Place of Event: Honolulu, HI, USA
Start-/End Date: 2009-04-18 - 2009-04-24

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Title: 17th Annual Meeting of the International Society for Magnetic Resonance in Medicine (ISMRM 2009)
Source Genre: Proceedings
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Pages: - Volume / Issue: - Sequence Number: 3300 Start / End Page: - Identifier: -