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  In-vivo T1 and T2* tissue-relaxation rates of H2O17 at 16.4 Tesla

Wiesner, H., Balla, D., Pohmann, R., Chen, W., Ugurbil, K., & Uludag, K. (2008). In-vivo T1 and T2* tissue-relaxation rates of H2O17 at 16.4 Tesla. Poster presented at ISMRM Workshop on High-Field Systems and Applications 2008: "Whats special about 7T+?", Toronto, Canada.

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ISMRM2008-Workshop-Rome-Wiesner_[0].pdf (Abstract), 60KB
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ISMRM2008-Workshop-Rome-Wiesner_[0].pdf
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 Creators:
Wiesner, HM1, 2, Author           
Balla, DZ1, 2, Author           
Pohmann, R1, 2, Author           
Chen , W, Author
Ugurbil, K, Author
Uludag, K1, 2, Author           
Affiliations:
1Former Department MRZ, Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_2528700              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, Spemannstrasse 38, 72076 Tübingen, DE, ou_1497794              

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 Abstract: The measurement of cerebral metabolic rate of oxygen (CMRO2) via direct NMR detection of the stable oxygen
isotope 17O is a promising tool to study alterations in brain activity and pathology. Due to the low natural
abundance of 0.037 H2O17, optimized acquisition parameters are crucial for 17O-weigthed MRI of metabolically
produced cerebral water. It has been suggested that signal-to-noise ratio increases almost quadratically with B0
due to field-independent quadrupolar interactions of 17O. Thus, in comparison to studies at lower field strengths the increased magnetization available at 16.4 T allows an enhanced spatial resolution and thus for the first time a tissue-specific determination of 17O relaxation.

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 Dates: 2008-10
 Publication Status: Issued
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 Identifiers: BibTex Citekey: 5698
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Title: ISMRM Workshop on High-Field Systems and Applications 2008: "Whats special about 7T+?"
Place of Event: Toronto, Canada
Start-/End Date: 2008-10-15 - 2008-10-17

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