English
 
User Manual Privacy Policy Disclaimer Contact us
  Advanced SearchBrowse

Item

ITEM ACTIONSEXPORT
  Velocity storage activity is affected after sustained centrifugation: a relationship with spatial disorientation

Nooij, S., Bos, J., & Groen, E. (2008). Velocity storage activity is affected after sustained centrifugation: a relationship with spatial disorientation. Experimental Brain Research, 190(2), 165-177. doi:10.1007/s00221-008-1460-3.

Item is

Basic

show hide
Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-C723-C Version Permalink: http://hdl.handle.net/21.11116/0000-0003-2FBF-3
Genre: Journal Article

Files

show Files

Locators

show

Creators

show
hide
 Creators:
Nooij, SAE1, Author              
Bos, JE, Author
Groen, EL, Author
Affiliations:
1External Organizations, ou_persistent22              

Content

show
hide
Free keywords: -
 Abstract: Prolonged exposure to hypergravity in a human centrifuge can lead to post-rotary spatial disorientation and motion sickness. These symptoms are mainly provoked by tilting head movements and resemble the Space Adaptation Syndrome. We hypothesized that the occurrence of these post-rotary effects might be related to changes in the velocity storage (VS) mechanism, which is suggested to play an important role in spatial orientation. In particular, we investigated whether the re-orientation of the eye velocity vector (EVV) towards gravity during off-vertical optokinetic stimulation was affected by centrifugation. Twelve human subjects were exposed to a hypergravity load of 3G (G-load directed along the naso-occipetal axis) for a duration of 90 min. Before and after centrifugation we recorded optokinetic nystagmus (OKN) elicited by a stimulus pattern moving about the subject’s yaw axis, with the head erect and tilted 45° to both sides. During OKN with the head erect, we observed a pitch-down component, reorienting the EVV on average 4.5° (SD 3.6, pretest values) away from the stimulus axis. Head tilt induced an additional shift of the EVV towards the spatial vertical of 6.4° on average (SD 3.2). This head-tilt induced reorientation was significantly decreased after centrifugation to 4.7° (SD 2.9), suggesting a reduction of VS-activity. By means of a vector model we estimated the reduction in VS-activity at 31. Such a decrease in VS-activity might reflect a deterioration of the ability to integrate sensory signals to obtain an estimate of gravity during tilting head movements, resulting in motion sickness in susceptible subjects.

Details

show
hide
Language(s):
 Dates: 2008-09
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1007/s00221-008-1460-3
BibTex Citekey: NooijBG2008
 Degree: -

Event

show

Legal Case

show

Project information

show

Source 1

show
hide
Title: Experimental Brain Research
  Other : Exp. Brain Res.
Source Genre: Journal
 Creator(s):
Affiliations:
Publ. Info: Heidelberg : Springer-Verlag
Pages: - Volume / Issue: 190 (2) Sequence Number: - Start / End Page: 165 - 177 Identifier: ISSN: 0014-4819
CoNE: https://pure.mpg.de/cone/journals/resource/954925398496