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  Smart Magnetic Resonance Imaging Agents that Sense Extracellular Calcium Fluctuations

Angelovski, G., Fousková, P., Mamedov, I., Canals, S., Tóth, É., & Logothetis, N. (2008). Smart Magnetic Resonance Imaging Agents that Sense Extracellular Calcium Fluctuations. ChemBioChem: A European Journal of Chemical Biology, 9(11), 1729-1734. doi:10.1002/cbic.200800165.

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Item Permalink: http://hdl.handle.net/11858/00-001M-0000-0013-C829-7 Version Permalink: http://hdl.handle.net/21.11116/0000-0003-3036-A
Genre: Journal Article

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 Creators:
Angelovski, G1, 2, Author              
Fousková, P, Author
Mamedov, I1, 2, Author              
Canals, S1, 2, Author              
Tóth, É, Author
Logothetis, NK1, 2, Author              
Affiliations:
1Department Physiology of Cognitive Processes, Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497798              
2Max Planck Institute for Biological Cybernetics, Max Planck Society, ou_1497794              

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 Abstract: Gd3+ chelates linked to a modified EGTA moiety were prepared in order to respond to extracellular Ca2+ fluctuations in the brain Gd3+ chelates linked to a modified EGTA moiety were prepared in order to respond to extracellular Ca2+ fluctuations in the brain. Upon interaction with Ca2+, they exhibit high and reversible relaxivity changes in buffered solution or in a model of the brain extracellular medium. These efficient Ca2+ magnetic resonance imaging sensors might open new perspectives in functional molecular imaging.

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 Dates: 2008-07
 Publication Status: Published in print
 Pages: -
 Publishing info: -
 Table of Contents: -
 Rev. Method: -
 Identifiers: DOI: 10.1002/cbic.200800165
BibTex Citekey: 5082
 Degree: -

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Title: ChemBioChem: A European Journal of Chemical Biology
  Other : ChemBioChem
Source Genre: Journal
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Publ. Info: Weinheim, Germany : Wiley-VCH
Pages: - Volume / Issue: 9 (11) Sequence Number: - Start / End Page: 1729 - 1734 Identifier: ISSN: 1439-4227
CoNE: https://pure.mpg.de/cone/journals/resource/110978984568897_1