ausblenden:
Schlagwörter:
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Zusammenfassung:
Gd3+ chelates linked to a modified EGTA moiety were prepared in order to
respond to extracellular Ca2+ fluctuations in the brain
Gd3+ chelates linked to a
modified EGTA moiety were prepared in order to respond to extracellular Ca2+
fluctuations in the brain. Upon interaction with Ca2+, they exhibit
high and reversible relaxivity changes in buffered solution or in a model of
the brain extracellular medium. These efficient Ca2+ magnetic
resonance imaging sensors might open new perspectives in functional molecular
imaging.
