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Abstract:
Lateral geniculate nucleus is a small-sized structure located in thalamus and targeted by predominant fraction of the retinal ganglion cells. That is, LGN, besides other cortical sub-cortical areas, is involved in the processing of visual information. Thus, previous fMRI studies successfully mapped activation in LGN despite its small size and quite poor BOLD response. In addition, we have recently shown a BOLD response to visual stimulation as short as 5ms in visual cortex. Our aim in this study was to characterize the BOLD response in the LGN at comparable short stimulus durations. Our findings were; a) with an appropriate design and adequate averaging a BOLD response to 10ms stimulus can be revealed in LGN b) BOLD responses in LGN exhibit non-linear behavior similar to that in visual cortex